EYLEA HD and EYLEA are administered by
injection into the eye. You should not use
EYLEA HD or EYLEA if you have an infection
in or around the eye, eye pain or redness, or
known allergies to any of the ingredients in
EYLEA HD or EYLEA, including aflibercept.

Injections into the eye with EYLEA HD or
EYLEA can result in an infection in the eye,
retinal detachment (separation of retina from
back of the eye) and, more rarely, serious
inflammation of blood vessels in the retina
that may include blockage. Call your doctor
right away if you experience eye pain or
redness, light sensitivity, or a change in vision
after an injection.

In some patients, injections with EYLEA HD
or EYLEA may cause a temporary increase in
eye pressure within 1 hour of the injection.
Sustained increases in eye pressure have been
reported with repeated injections, and your
doctor may monitor this after each injection.

There is a potential but rare risk of serious
and sometimes fatal side effects, related to
blood clots, leading to heart attack or stroke
in patients receiving EYLEA HD or EYLEA.

The most common side effects reported in
patients receiving EYLEA HD were cataract,
increased redness in the eye, increased
pressure in the eye, eye discomfort, pain,
or irritation, blurred vision, vitreous (gel-like
substance) floaters, vitreous detachment,
injury to the outer layer of the eye,
and bleeding in the back of the eye.

The most common side effects reported in
patients receiving EYLEA were increased
redness in the eye, eye pain, cataract, vitreous
detachment, vitreous floaters, moving spots
in the field of vision, and increased pressure
in the eye.

You may experience temporary visual changes
after an EYLEA HD or EYLEA injection and
associated eye exams; do not drive or use
machinery until your vision recovers
sufficiently.

For additional safety information, please talk
to your doctor and see the full Prescribing
Information for EYLEA HD and EYLEA.

IMPORTANT SAFETY INFORMATION

INDICATIONS